TFB2M antibody (AA 10-386) (Cy3)

Catalog No. ABIN8047887

The Rabbit Polyclonal anti-TFB2M antibody is suitable to detect TFB2M in samples from Human. It has been validated for FACS.

Quick Overview for TFB2M antibody (AA 10-386) (Cy3) (ABIN8047887)

Target: TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TFB2M antibody is conjugated to Cy3

Application: Flow Cytometry (FACS)

Product Details anti-TFB2M Antibody (Cy3)

Binding Specificity: AA 10-386

Purpose: Anti-TFB2M Antibody Cy3 Conjugated

Cross-Reactivity (Details): No cross reactivity with other proteins.

Predicted Reactivity: Human TFB2M shares 53.2%,54.8% amino acid (aa) sequence identity with mouse,rat TFB2M,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TFB2M recombinant protein (Position: R10-K386). Human TFB2M shares 53.2% and 54.8% amino acid (aa) sequence identity with mouse and rat TFB2M, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TFB2M

Target: TFB2M (Transcription Factor B2, Mitochondrial (TFB2M))

Alternative Name: TFB2M

Background:

Background: Dimethyladenosine transferase 2, transcription factor B2, mitochondrial is an enzyme that in humans is encoded by the TFB2M gene. S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA atthe conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction withPOLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity. Compared to TFB1M, itactivates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity

Gene Full Name: transcription factor B2, mitochondrial

Gene ID: 64216

UniProt: Q9H5Q4