SGPL1 antibody (AA 301-400)

Catalog No. ABIN755128

This Rabbit Polyclonal antibody specifically detects SGPL1 in ELISA, IHC (p), FACS, IF (cc), IF (p) and IHC (fro). It exhibits reactivity toward Human, Mouse and Ratand has been mentioned in 1 publication.

Quick Overview for SGPL1 antibody (AA 301-400) (ABIN755128)

Target: SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGPL1 antibody is un-conjugated

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-SGPL1 Antibody

Binding Specificity: AA 301-400

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SGPL1

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

References for anti-SGPL1 antibody (ABIN755128)

Choi, de Poot, Lee, Kim, Han, Kim, Finley, Lee: "Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation." in: Nature communications, Vol. 7, pp. 10963, (2016) (PubMed).

Target Details for SGPL1

Target: SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))

Alternative Name: SGPL1

Background:

Synonyms: SPL, S1PL, Sphingosine-1-phosphate lyase 1, SP-lyase 1, SPL 1, hSPL, Sphingosine-1-phosphate aldolase, SGPL1, KIAA1252

Background: Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis.

Gene ID: 8879

UniProt: O95470

Pathways: Platelet-derived growth Factor Receptor Signaling