TKT antibody (AA 1-116) (HRP)

Catalog No. ABIN8048619

The Mouse Monoclonal anti-TKT antibody is suitable to detect TKT in samples from Human, Rat and Mouse. It has been validated for WB, IHC and ELISA.

Quick Overview for TKT antibody (AA 1-116) (HRP) (ABIN8048619)

Target: TKT (Transketolase (TKT))

Reactivity: Human, Rat, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This TKT antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Clone: 2I3

Product Details anti-TKT Antibody (HRP)

Binding Specificity: AA 1-116

Purpose: Anti-Transketolase/TKT Antibody (monoclonal, 2I3) HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human Transketolase/TKT recombinant protein (Position: M1-A116).

Isotype: IgG2b

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TKT

Target: TKT (Transketolase (TKT))

Alternative Name: TKT

Background:

Background: Transketolase is a thiamine-dependent enzyme that links the pentose phosphate pathway with the glycolytic pathway. The pentose phosphate pathway, which is active in most tissues, provides sugar phosphates for intermediary biosynthesis, especially nucleotide metabolism, and generates the biosynthetic reducing power for the cell in the form of NADPH. Transketolase is ly involved in the branch of the pathway that channels excess sugar phosphates to glycolysis, enabling the production of NADPH to be maintained under different metabolic conditions. NADPH is critical for maintaining cerebral glutathione, and thus it is likely that transketolase plays an important role in brain metabolism.

Gene Full Name: transketolase

Gene ID: 7086

UniProt: P29401