TIMM50 antibody (AA 8-324) (HRP)

Catalog No. ABIN8048685

The Rabbit Polyclonal anti-TIMM50 antibody is suitable to detect TIMM50 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for TIMM50 antibody (AA 8-324) (HRP) (ABIN8048685)

Target: TIMM50 (Translocase of Inner Mitochondrial Membrane 50 Homolog (TIMM50))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TIMM50 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-TIMM50 Antibody (HRP)

Binding Specificity: AA 8-324

Purpose: Anti-TIMM50 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TIMM50 shares 92.7% amino acid (aa) sequence identity with mouse TIMM50.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TIMM50 recombinant protein (Position: F8-Q324). Human TIMM50 shares 92.7% amino acid (aa) sequence identity with mouse TIMM50.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TIMM50

Target: TIMM50 (Translocase of Inner Mitochondrial Membrane 50 Homolog (TIMM50))

Alternative Name: TIMM50

Background:

Background: This gene encodes a subunit of the TIM23 inner mitochondrial membrane translocase complex. The encoded protein functions as the receptor subunit that recognizes the mitochondrial targeting signal, or presequence, on protein cargo that is destined for the mitochondrial inner membrane and matrix. This protein may also play a role in maintaining the membrane permeability barrier, and knockdown of this gene in human cells results in the release of cytochrome c and apoptosis.

Gene Full Name: translocase of inner mitochondrial membrane 50

Gene ID: 92609

UniProt: Q3ZCQ8