TRAM1 antibody (C-Term) (HRP)

Catalog No. ABIN8048784

The Rabbit Polyclonal anti-TRAM1 antibody is suitable to detect TRAM1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for TRAM1 antibody (C-Term) (HRP) (ABIN8048784)

Target: TRAM1 (Translocation Associated Membrane Protein 1 (TRAM1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRAM1 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-TRAM1 Antibody (HRP)

Binding Specificity: C-Term

Purpose: Anti-TRAM1 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: identical to the related rat,mouse sequences.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TRAM1, identical to the related rat and mouse sequences.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TRAM1

Target: TRAM1 (Translocation Associated Membrane Protein 1 (TRAM1))

Alternative Name: TRAM1

Background:

Background: TRAM1 (Translocation-Associating Membrane Protein 1), By crosslinking and reconstitution of canine proteoliposomes, followed by microsequencing and PCR screening of canine kidney and HeLa cell cDNA libraries, Gorlich et al. (1992) isolated cDNAs encoding TRAM (translocating chain-associating membrane protein). The International Radiation Hybrid Mapping Consortium mapped the TRAM gene to chromosome 8. Sequence analysis predicted that human TRAM is a 374-amino acid, 8-pass transmembrane protein that shares 95 % amino acid identity with the canine protein. Functional analysis indicated that TRAM influences glycosylation and is stimulatory or required for the translocation of secretory proteins.

Gene Full Name: translocation associated membrane protein 1

Sequence Similarities: Belongs to the TRAM family.

Gene ID: 23471

UniProt: Q15629