TMBIM1 antibody (N-Term) (Fluoro488)

Catalog No. ABIN8048857

The Fluoro488-conjugated Rabbit Polyclonal anti-TMBIM1 antibody (ABIN8048857) specifically detects TMBIM1 in WB, IHC and FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TMBIM1 antibody (N-Term) (Fluoro488) (ABIN8048857)

Target: TMBIM1 (Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMBIM1 antibody is conjugated to Fluoro488

Application: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-TMBIM1 Antibody (Fluoro488)

Binding Specificity: N-Term

Purpose: Anti-TMBIM1 Antibody Fluoro488 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human TMBIM1, which shares 87.5% and 93.8% amino acid (aa) sequence identity with mouse and rat TMBIM1, respectively.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Comment:

Applications are recommended based on the unconjugated antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TMBIM1

Target: TMBIM1 (Transmembrane BAX Inhibitor Motif Containing 1 (TMBIM1))

Alternative Name: TMBIM1

Background:

Background: Transmembrane BAX inhibitor motif-containing protein 1 is a protein that in humans is encoded by the TMBIM1 gene. TMBIM1 is a member of the 7 TMS (7 transmembrane domains) family of receptors known to mediate the activation of various transcription factors. TMBIM1 is identified as a novel modulator of NF-kB activation. A drosophila homolog of this protein (dNMDA1 with 40 % homology to hTMBIM1) is reported to be unregulated during aging and oxidative stress.

Gene Full Name: transmembrane BAX inhibitor motif containing 1

Gene ID: 64114

UniProt: Q969X1