TMC6 antibody (AA 1-772) (HRP)

Catalog No. ABIN8048883

The Rabbit Polyclonal anti-TMC6 antibody is suitable to detect TMC6 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for TMC6 antibody (AA 1-772) (HRP) (ABIN8048883)

Target: TMC6 (Transmembrane Channel-Like 6 (TMC6))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMC6 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-TMC6 Antibody (HRP)

Binding Specificity: AA 1-772

Purpose: Anti-TMC6 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TMC6 shares 76.7% amino acid (aa) sequence identity with mouse TMC6.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TMC6 recombinant protein (Position: M1-H772). Human TMC6 shares 76.7% amino acid (aa) sequence identity with mouse TMC6.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TMC6

Target: TMC6 (Transmembrane Channel-Like 6 (TMC6))

Alternative Name: TMC6

Background:

Background: Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 10 transmembrane domains and 2 leucine zipper motifs.

Gene Full Name: transmembrane channel like 6

Gene ID: 11322

UniProt: Q7Z403