TMED10 antibody (AA 27-194) (APC)

Catalog No. ABIN8048950

The APC-conjugated Rabbit Polyclonal anti-TMED10 antibody (ABIN8048950) specifically detects TMED10 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TMED10 antibody (AA 27-194) (APC) (ABIN8048950)

Target: TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMED10 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-TMED10 Antibody (APC)

Binding Specificity: AA 27-194

Purpose: Anti-TMP21/TMED10 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TMP21,TMED10 shares 97% amino acid (aa) sequence identity with both mouse,rat TMP21,TMED10.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TMP21/TMED10 recombinant protein (Position: R27-M194). Human TMP21/TMED10 shares 97% amino acid (aa) sequence identity with both mouse and rat TMP21/TMED10.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TMED10

Target: TMED10 (Transmembrane Emp24-Like Trafficking Protein 10 (TMED10))

Alternative Name: TMED10

Background:

Background: This gene is a member of the EMP24/GP25L/p24 family and encodes a protein with a GOLD domain. This type I membrane protein is localized to the plasma membrane and golgi cisternae and is involved in vesicular protein trafficking. The protein is also a member of a heteromeric secretase complex and regulates the complex's gamma-secretase activity without affecting its epsilon-secretase activity. Mutations in this gene have been associated with early-onset familial Alzheimer's disease. This gene has a pseudogene on chromosome 8.

Gene Full Name: transmembrane p24 trafficking protein 10

Gene ID: 10972

UniProt: P49755