TMPRSS4 antibody (AA 1-369) (Fluoro550)

Catalog No. ABIN8048979

The Rabbit Polyclonal anti-TMPRSS4 antibody is suitable to detect TMPRSS4 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for TMPRSS4 antibody (AA 1-369) (Fluoro550) (ABIN8048979)

Target: TMPRSS4 (Transmembrane Protease, serine 4 (TMPRSS4))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMPRSS4 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-TMPRSS4 Antibody (Fluoro550)

Binding Specificity: AA 1-369

Purpose: Anti-TMPRSS4 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TMPRSS4 shares 76.4% amino acid (aa) sequence identity with mouse TMPRSS4.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TMPRSS4 recombinant protein (Position: M1-K369). Human TMPRSS4 shares 76.4% amino acid (aa) sequence identity with mouse TMPRSS4.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TMPRSS4

Target: TMPRSS4 (Transmembrane Protease, serine 4 (TMPRSS4))

Alternative Name: TMPRSS4

Background:

Background: This gene encodes a member of the serine protease family. Serine proteases are known to be involved in a variety of biological processes, whose malfunction often leads to human diseases and disorders. This gene was identified as a gene overexpressed in pancreatic carcinoma. The encoded protein is membrane bound with a N-terminal anchor sequence and a glycosylated extracellular region containing the serine protease domain. The protein has been found to promote SARS-CoV-2 entry into host cells.

Gene Full Name: transmembrane serine protease 4

Gene ID: 56649

UniProt: Q9NRS4