TMEM52B antibody (AA 22-183) (Biotin)

Catalog No. ABIN8049175

The Biotin-conjugated Rabbit Polyclonal anti-TMEM52B antibody (ABIN8049175) specifically detects TMEM52B in ELISA, WB and IHC. The antibody is reactive with Human, Mouse, Rat and Monkey samples.

Quick Overview for TMEM52B antibody (AA 22-183) (Biotin) (ABIN8049175)

Target: TMEM52B (Transmembrane Protein 52B (TMEM52B))

Reactivity: Human, Mouse, Rat, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TMEM52B antibody is conjugated to Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-TMEM52B Antibody (Biotin)

Binding Specificity: AA 22-183

Purpose: Anti-TMEM52B Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TMEM52B recombinant protein (Position: T22-N183).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TMEM52B

Target: TMEM52B (Transmembrane Protein 52B (TMEM52B))

Alternative Name: TMEM52B

Background:

Background: TMEM52B (Transmembrane Protein 52B, also known as C12orf59) is a Protein Coding gene. The TMEM52B gene, located on 12p13.2, is conserved in chimpanzee, dog, cow, mouse, rat, chicken, and frog. 2 alternatively spliced human isoforms have been reported. The 183-amino acid protein has a reported mass of 20,002 daltons. The cellular localization is predicted to be membrane-associated. C12orf59 might act as a potential oncogenic protein in gastric cancer (GC). Researchers propose that the decreased C12orf59 expression status is a prognostic biomarker of ccRCC and cooperates with the loss of von Hippel-Lindau (VHL) all the while promoting renal carcinogenesis. 192 organisms have orthologs with human gene TMEM52B.

Gene Full Name: transmembrane protein 52B

Gene ID: 120939

UniProt: Q4KMG9