TCOF1 antibody (AA 1-1340) (Fluoro647)

Catalog No. ABIN8049338

This Rabbit Polyclonal antibody specifically detects TCOF1 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TCOF1 antibody (AA 1-1340) (Fluoro647) (ABIN8049338)

Target: TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCOF1 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-TCOF1 Antibody (Fluoro647)

Binding Specificity: AA 1-1340

Purpose: Anti-TCOF1 Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TCOF1 recombinant protein (Position: M1-K1340).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TCOF1

Target: TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))

Alternative Name: TCOF1

Background:

Background: This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: treacle ribosome biogenesis factor 1

Gene ID: 6949

UniProt: Q13428