TCOF1 antibody (AA 1-1340)

Catalog No. ABIN8049339

The Rabbit Polyclonal anti-TCOF1 antibody is suitable to detect TCOF1 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA, IF, FACS and ICC.

Quick Overview for TCOF1 antibody (AA 1-1340) (ABIN8049339)

Target: TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TCOF1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Grade: Carrier-free

Product Details anti-TCOF1 Antibody

Binding Specificity: AA 1-1340

Purpose: Anti-TCOF1 Antibody

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-TCOF1 Antibody. Tested in WB, ICC, IF, Flow Cytometry, ELISA applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TCOF1 recombinant protein (Position: M1-K1340).

Isotype: IgG

Application Details

Application Notes: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TCOF1

Target: TCOF1 (Treacher Collins-Franceschetti Syndrome 1 (TCOF1))

Alternative Name: TCOF1

Background:

Background: This gene encodes a nucleolar protein with a LIS1 homology domain. The protein is involved in ribosomal DNA gene transcription through its interaction with upstream binding factor (UBF). Mutations in this gene have been associated with Treacher Collins syndrome, a disorder which includes abnormal craniofacial development. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: treacle ribosome biogenesis factor 1

Molecular Weight: 250 kDa

Gene ID: 6949

UniProt: Q13428