TRIM2 antibody (AA 78-398) (Fluoro594)

Catalog No. ABIN8049685

The Fluoro594-conjugated Rabbit Polyclonal anti-TRIM2 antibody (ABIN8049685) specifically detects TRIM2 in FACS. The antibody is reactive with Human, Mouse and Rat samples.

Quick Overview for TRIM2 antibody (AA 78-398) (Fluoro594) (ABIN8049685)

Target: TRIM2 (Tripartite Motif Containing 2 (TRIM2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM2 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-TRIM2 Antibody (Fluoro594)

Binding Specificity: AA 78-398

Purpose: Anti-TRIM2 Antibody Fluoro594 Conjugated

Predicted Reactivity: Human TRIM2 shares 99.4%,98.8% amino acid (aa) sequence identity with mouse,rat TRIM2,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TRIM2 recombinant protein (Position: Q78-E398). Human TRIM2 shares 99.4% and 98.8% amino acid (aa) sequence identity with mouse and rat TRIM2, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TRIM2

Target: TRIM2 (Tripartite Motif Containing 2 (TRIM2))

Alternative Name: TRIM2

Background:

Background: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. It plays a neuroprotective role and functions as an E3-ubiquitin ligase in proteasome-mediated degradation of target proteins. Mutations in this gene can cause early-onset axonal neuropathy. Alternative splicing results in multiple transcript variants.

Gene Full Name: tripartite motif containing 2

Gene ID: 23321

UniProt: Q9C040