TRIM23 antibody (AA 35-406) (Fluoro594)

Catalog No. ABIN8049707

This Rabbit Polyclonal antibody specifically detects TRIM23 in FACS. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for TRIM23 antibody (AA 35-406) (Fluoro594) (ABIN8049707)

Target: TRIM23 (Tripartite Motif Containing 23 (TRIM23))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM23 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-TRIM23 Antibody (Fluoro594)

Binding Specificity: AA 35-406

Purpose: Anti-TRIM23 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TRIM23 shares 97.3% amino acid (aa) sequence identity with mouse TRIM23.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TRIM23 recombinant protein (Position: E35-R406). Human TRIM23 shares 97.3% amino acid (aa) sequence identity with mouse TRIM23.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TRIM23

Target: TRIM23 (Tripartite Motif Containing 23 (TRIM23))

Alternative Name: TRIM23

Background:

Background: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein is also a member of the ADP ribosylation factor family of guanine nucleotide-binding family of proteins. Its carboxy terminus contains an ADP-ribosylation factor domain and a guanine nucleotide binding site, while the amino terminus contains a GTPase activating protein domain which acts on the guanine nucleotide binding site. The protein localizes to lysosomes and the Golgi apparatus. It plays a role in the formation of intracellular transport vesicles, their movement from one compartment to another, and phopholipase D activation. Three alternatively spliced transcript variants for this gene have been described.

Gene Full Name: tripartite motif containing 23

Gene ID: 373

UniProt: P36406