TRIM25 antibody (AA 1-590) (Fluoro647)

Catalog No. ABIN8049756

The Rabbit Polyclonal anti-TRIM25 antibody is suitable to detect TRIM25 in samples from Mouse and Rat. It has been validated for FACS.

Quick Overview for TRIM25 antibody (AA 1-590) (Fluoro647) (ABIN8049756)

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM25 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-TRIM25 Antibody (Fluoro647)

Binding Specificity: AA 1-590

Purpose: Anti-TRIM25/EFP Antibody Fluoro647 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse TRIM25/EFP recombinant protein (Position: M1-H590).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TRIM25

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Alternative Name: Trim25

Background:

Background: Tripartite motif-containing protein 25 is a protein that in humans is encoded by the TRIM25 gene. It is mapped to 17q22. The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene.

Gene Full Name: tripartite motif-containing 25

Gene ID: 217069

UniProt: Q61510