TRIM63 antibody (AA 2-329) (APC)

Catalog No. ABIN8049986

This Rabbit Polyclonal antibody specifically detects TRIM63 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TRIM63 antibody (AA 2-329) (APC) (ABIN8049986)

Target: TRIM63 (Tripartite Motif Containing 63 (TRIM63))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRIM63 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-TRIM63 Antibody (APC)

Binding Specificity: AA 2-329

Purpose: Anti-MURF1/TRIM63 Antibody APC Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human MURF1/TRIM63 recombinant protein (Position: D2-E329).

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for TRIM63

Target: TRIM63 (Tripartite Motif Containing 63 (TRIM63))

Alternative Name: TRIM63

Background:

Background: E3 ubiquitin-protein ligase TRIM63 is an enzyme that in humans is encoded by the TRIM63 gene. This gene encodes a member of the RING zinc finger protein family found in striated muscle and iris. The product of this gene is an E3 ubiquitin ligase that localizes to the Z-line and M-line lattices of myofibrils. This protein plays an important role in the atrophy of skeletal and cardiac muscle and is required for the degradation of myosin heavy chain proteins, myosin light chain, myosin binding protein, and for muscle-type creatine kinase.

Gene Full Name: tripartite motif containing 63

Gene ID: 84676

UniProt: Q969Q1