Dnmt2 antibody (AA 16-391) (Fluoro594)

Catalog No. ABIN8050072

The Fluoro594-conjugated Rabbit Polyclonal anti-Dnmt2 antibody (ABIN8050072) specifically detects Dnmt2 in FACS. The antibody is reactive with Mouse and Rat samples.

Quick Overview for Dnmt2 antibody (AA 16-391) (Fluoro594) (ABIN8050072)

Target: Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Dnmt2 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Product Details anti-Dnmt2 Antibody (Fluoro594)

Binding Specificity: AA 16-391

Purpose: Anti-DNMT2/TRDMT1 Antibody Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Mouse DNMT2,TRDMT1 shares 80.6%,88% amino acid (aa) sequence identity with human,rat DNMT2,TRDMT1,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse DNMT2/TRDMT1 recombinant protein (Position: M16-E391). Mouse DNMT2/TRDMT1 shares 80.6% and 88% amino acid (aa) sequence identity with human and rat DNMT2/TRDMT1, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for Dnmt2

Target: Dnmt2 (TRDMT1) (tRNA Aspartic Acid Methyltransferase 1 (TRDMT1))

Alternative Name: TRDMT1

Background:

Background: Enables tRNA (cytidine-5-)-methyltransferase activity. Involved in tRNA methylation and tRNA stabilization. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system, genitourinary system, hemolymphoid system gland, olfactory epithelium, and thyroid gland. Orthologous to human TRDMT1 (tRNA aspartic acid methyltransferase 1).

Gene Full Name: tRNA aspartic acid methyltransferase 1

Gene ID: 13434

UniProt: O55055