Trnt1 antibody (AA 1-410) (Biotin)

Catalog No. ABIN8050156

The Biotin-conjugated Rabbit Polyclonal anti-Trnt1 antibody (ABIN8050156) specifically detects Trnt1 in WB, ELISA and IHC. The antibody is reactive with Human samples.

Quick Overview for Trnt1 antibody (AA 1-410) (Biotin) (ABIN8050156)

Target: Trnt1 (tRNA Nucleotidyl Transferase, CCA-Adding, 1 (Trnt1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Trnt1 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-Trnt1 Antibody (Biotin)

Binding Specificity: AA 1-410

Purpose: Anti-TRNT1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TRNT1 recombinant protein (Position: M1-Q410).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for Trnt1

Target: Trnt1 (tRNA Nucleotidyl Transferase, CCA-Adding, 1 (Trnt1))

Alternative Name: TRNT1

Background:

Background: tRNA-nucleotidyltransferase 1, is an enzyme that in humans is encoded by the TRNT1 gene. The protein encoded by this gene is a CCA-adding enzyme which belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. This essential enzyme functions by catalyzing the addition of the conserved nucleotide triplet CCA to the 3' terminus of tRNA molecules. Mutations in this gene result in sideroblastic anemia with B-cell immunodeficiency, periodic fevers, and developmental delay. Alternative splicing results in multiple transcript variants.

Gene Full Name: tRNA nucleotidyl transferase 1

Gene ID: 51095

UniProt: Q96Q11