TDO2 antibody (AA 16-406) (HRP)

Catalog No. ABIN8050295

This Rabbit Polyclonal antibody specifically detects TDO2 in WB, IHC and ELISA. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for TDO2 antibody (AA 16-406) (HRP) (ABIN8050295)

Target: TDO2 (Tryptophan 2,3-Dioxygenase (TDO2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TDO2 antibody is conjugated to HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-TDO2 Antibody (HRP)

Binding Specificity: AA 16-406

Purpose: Anti-TDO2 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human TDO2 shares 89.3% amino acid (aa) sequence identity with both mouse,rat TDO2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human TDO2 recombinant protein (Position: K16-D406). Human TDO2 shares 89.3% amino acid (aa) sequence identity with both mouse and rat TDO2.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for TDO2

Target: TDO2 (Tryptophan 2,3-Dioxygenase (TDO2))

Alternative Name: TDO2

Background:

Background: This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism.

Gene Full Name: tryptophan 2,3-dioxygenase

Gene ID: 6999

UniProt: P48775