UCHL3 antibody (AA 1-223) (Fluoro550)

Catalog No. ABIN8051989

The Fluoro550-conjugated Rabbit Polyclonal anti-UCHL3 antibody (ABIN8051989) specifically detects UCHL3 in FACS. The antibody is reactive with Human, Rat and Mouse samples.

Quick Overview for UCHL3 antibody (AA 1-223) (Fluoro550) (ABIN8051989)

Target: UCHL3 (Uchl3) (Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) (Uchl3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UCHL3 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-UCHL3 Antibody (Fluoro550)

Binding Specificity: AA 1-223

Purpose: Anti-UCHL3 Antibody Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human UCHL3 shares 98.2%,97.8% amino acid (aa) sequence identity with mouse,rat UCHL3,respectively.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human UCHL3 recombinant protein (Position: M1-N223). Human UCHL3 shares 98.2% and 97.8% amino acid (aa) sequence identity with mouse and rat UCHL3, respectively.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for UCHL3

Target: UCHL3 (Uchl3) (Ubiquitin Carboxyl-terminal Esterase L3 (Ubiquitin Thiolesterase) (Uchl3))

Alternative Name: UCHL3

Background:

Background: The protein encoded by this gene is a member of the deubiquitinating enzyme family. Members of this family are proteases that catalyze the removal of ubiquitin from polypeptides and are divided into five classes, depending on the mechanism of catalysis. This protein may hydrolyze the ubiquitinyl-N-epsilon amide bond of ubiquitinated proteins to regenerate ubiquitin for another catalytic cycle. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Gene Full Name: ubiquitin C-terminal hydrolase L3

Gene ID: 7347

UniProt: P15374

Pathways: Feeding Behaviour, Positive Regulation of fat Cell Differentiation