UBD antibody (AA 1-163) (Biotin)

Catalog No. ABIN8052019

The Biotin-conjugated Rabbit Polyclonal anti-UBD antibody (ABIN8052019) specifically detects UBD in WB, IHC and ELISA. The antibody is reactive with Human samples.

Quick Overview for UBD antibody (AA 1-163) (Biotin) (ABIN8052019)

Target: UBD (Ubiquitin D (UBD))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UBD antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-UBD Antibody (Biotin)

Binding Specificity: AA 1-163

Purpose: Anti-FAT10/UBD Antibody Biotin Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human FAT10/UBD recombinant protein (Position: M1-I163).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for UBD

Target: UBD (Ubiquitin D (UBD))

Alternative Name: UBD

Background:

Background: Ubiquitin D is a protein that in humans is encoded by the UBD gene. It is mapped to 6p22.1. This gene encodes a protein which contains two ubiquitin-like domains and appears to have similar function to ubiquitin. Through covalent attachment, the encoded protein targets other proteins for 26S proteasome degradation. This protein has been implicated to function in many cellular processes, including caspase-dependent apoptosis, formation of aggresomes, mitotic regulation, and dendritic cell maturation. Upregulation of this gene may promote inflammation in chronic kidney disease and has been observed in many cancer types.

Gene Full Name: ubiquitin like modifier D

Gene ID: 10537

UniProt: O15205

Pathways: Ubiquitin Proteasome Pathway