USP14 antibody (AA 23-427) (HRP)

Catalog No. ABIN8052159

The Rabbit Polyclonal anti-USP14 antibody is suitable to detect USP14 in samples from Human, Mouse and Rat. It has been validated for WB, ELISA and IHC.

Quick Overview for USP14 antibody (AA 23-427) (HRP) (ABIN8052159)

Target: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This USP14 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-USP14 Antibody (HRP)

Binding Specificity: AA 23-427

Purpose: Anti-USP14 Antibody HRP Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human USP14 shares 96.3% amino acid (aa) sequence identity with mouse USP14.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human USP14 recombinant protein (Position: D23-Q427). Human USP14 shares 96.3% amino acid (aa) sequence identity with mouse USP14.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for USP14

Target: USP14 (Ubiquitin Specific Peptidase 14 (USP14))

Alternative Name: USP14

Background:

Background: This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene Full Name: ubiquitin specific peptidase 14

Gene ID: 9097

UniProt: P54578