UGT1A1 antibody (AA 57-248) (Biotin)

Catalog No. ABIN8052586

The Biotin-conjugated Rabbit Polyclonal anti-UGT1A1 antibody (ABIN8052586) specifically detects UGT1A1 in WB, IHC and ELISA. The antibody is reactive with Mouse and Rat samples.

Quick Overview for UGT1A1 antibody (AA 57-248) (Biotin) (ABIN8052586)

Target: UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This UGT1A1 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-UGT1A1 Antibody (Biotin)

Binding Specificity: AA 57-248

Purpose: Anti-Ugt1a1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived mouse Ugt1a1 recombinant protein (Position: H57-D248).

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for UGT1A1

Target: UGT1A1 (UDP Glucuronosyltransferase 1 Family, Polypeptide A1 (UGT1A1))

Alternative Name: Ugt1a1

Background:

Background: UDP-glucuronosyltransferase 1-1 also known as UGT-1A is an enzyme that in humans is encoded by the UGT1A1 gene. Predicted to enable several functions, including glucuronosyltransferase activity, protein dimerization activity, and retinoic acid binding activity. Predicted to be involved in several processes, including biphenyl catabolic process, cellular glucuronidation, and negative regulation of cellular glucuronidation. Is integral component of plasma membrane. Part of endoplasmic reticulum chaperone complex. Is expressed in alimentary system, nervous system, and urinary system. Human ortholog(s) of this gene implicated in several diseases, including bilirubin metabolic disorder (multiple), cholecystolithiasis, cholelithiasis, female reproductive organ cancer (multiple), and hepatitis B. Orthologous to human UGT1A1 (UDP glucuronosyltransferase family 1 member A1).

Gene Full Name: UDP glucuronosyltransferase 1 family, polypeptide A1

Gene ID: 394436

UniProt: Q63886

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha