GALNT2 antibody (AA 442-571) (Fluoro647)

Catalog No. ABIN8052717

The Rabbit Polyclonal anti-GALNT2 antibody is suitable to detect GALNT2 in samples from Human and Rat. It has been validated for FACS.

Quick Overview for GALNT2 antibody (AA 442-571) (Fluoro647) (ABIN8052717)

Target: GALNT2 (UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 2 (GalNAc-T2) (GALNT2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GALNT2 antibody is conjugated to Fluoro647

Application: Flow Cytometry (FACS)

Product Details anti-GALNT2 Antibody (Fluoro647)

Binding Specificity: AA 442-571

Purpose: Anti-GALNT2 Antibody Fluoro647 Conjugated

Predicted Reactivity: Human GALNT2 shares 96.9% amino acid (aa) sequence identity with mouse GALNT2.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human GALNT2 recombinant protein (Position: H442-Q571). Human GALNT2 shares 96.9% amino acid (aa) sequence identity with mouse GALNT2.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for GALNT2

Target: GALNT2 (UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 2 (GalNAc-T2) (GALNT2))

Alternative Name: GALNT2

Background:

Background: Polypeptide N-acetylgalactosaminyltransferase 2 is an enzyme that in humans is encoded by the GALNT2 gene. This gene encodes a member of the glycosyltransferase 2 protein family. Members of this family initiate mucin-type O-glycoslation of peptides in the Golgi apparatus. The encoded protein may be involved in O-linked glycosylation of the immunoglobulin A1 hinge region. This gene may influence triglyceride levels, and may be involved Type 2 diabetes, as well as several types of cancer. Alternative splicing results in multiple transcript variants.

Gene Full Name: polypeptide N-acetylgalactosaminyltransferase 2

Gene ID: 2590

UniProt: Q10471

Pathways: Production of Molecular Mediator of Immune Response