MYB antibody (AA 1-201) (Fluoro550)

Catalog No. ABIN8053074

The Rabbit Polyclonal anti-MYB antibody is suitable to detect MYB in samples from Human. It has been validated for FACS.

Quick Overview for MYB antibody (AA 1-201) (Fluoro550) (ABIN8053074)

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MYB antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Product Details anti-MYB Antibody (Fluoro550)

Binding Specificity: AA 1-201

Purpose: Anti-c-Myb Antibody Fluoro550 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human c-Myb shares 100% amino acid (aa) sequence identity with mouse c-Myb.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human c-Myb recombinant protein (Position: M1-E201). Human c-Myb shares 100% amino acid (aa) sequence identity with mouse c-Myb.

Isotype: IgG

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for MYB

Target: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Alternative Name: MYB

Background:

Background: Myb proto-oncogene protein, also known as transcriptional activator Myb, is a protein that in humans is encoded by the MYB gene. It is a member of the MYB (myeloblastosis) family of transcription factors. This gene is mapped to 6q23.3.The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis, including the regulation of miR-155 in B-cells. MYB is also a critical target of MIR150.

Gene Full Name: MYB proto-oncogene, transcription factor

Sequence Similarities: Contains 3 HTH myb-type DNA-binding domains.

Gene ID: 4602

UniProt: P10242

Pathways: Chromatin Binding, Positive Regulation of Immune Effector Process