VSX2 antibody (AA 249-361) (HRP)

Catalog No. ABIN8053715

This Rabbit Polyclonal antibody specifically detects VSX2 in WB, ELISA and IHC. It exhibits reactivity toward Human and Mouse.

Quick Overview for VSX2 antibody (AA 249-361) (HRP) (ABIN8053715)

Target: VSX2 (Visual System Homeobox 2 (VSX2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VSX2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Product Details anti-VSX2 Antibody (HRP)

Binding Specificity: AA 249-361

Purpose: Anti-CHX10/VSX2 Antibody HRP Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: coli-derived human CHX10 recombinant protein (Position: A249-A361). Human CHX10 shares 90.3% amino acid (aa) sequence identity with mouse CHX10.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human CHX10 recombinant protein (Position: A249-A361). Human CHX10 shares 90.3% amino acid (aa) sequence identity with mouse CHX10.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for VSX2

Target: VSX2 (Visual System Homeobox 2 (VSX2))

Alternative Name: VSX2

Background:

Background: Visual system homeobox 2 is a protein that in humans is encoded by the VSX2 gene. This gene encodes a homeobox protein originally described as a retina-specific transcription factor. Mutations in this gene are associated with microphthalmia, cataracts and iris abnormalities. In situ hybridization to human fetal retinal sections detected CHX10 expression in retinal neuroblasts at all stages examined. Human CHX10 is expressed in progenitor cells of the developing neuroretina and in the inner nuclear layer of the mature retina.

Gene Full Name: visual system homeobox 2

Gene ID: 338917

UniProt: P58304

Pathways: Dopaminergic Neurogenesis