VWF antibody (AA 2535-2813) (Fluoro594)

Catalog No. ABIN8053856

This Rabbit Polyclonal antibody specifically detects VWF in IHC, WB, FACS, ICC and IHC (fro). It exhibits reactivity toward Human.

Quick Overview for VWF antibody (AA 2535-2813) (Fluoro594) (ABIN8053856)

Target: VWF (Von Willebrand Factor (VWF))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VWF antibody is conjugated to Fluoro594

Application: Immunohistochemistry (IHC), Western Blotting (WB), Flow Cytometry (FACS), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-VWF Antibody (Fluoro594)

Binding Specificity: AA 2535-2813

Purpose: Anti-Von Willebrand Factor/VWF Antibody Fluoro594 Conjugated

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Predicted Reactivity: Human VWF shares 79% amino acid (aa) sequence identity with mouse VWF.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human VWF recombinant protein (Position: R2535-K2813). Human VWF shares 79% amino acid (aa) sequence identity with mouse VWF.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL Immunohistochemistry (Frozen Section), 0.5-1 μg/mL Immunocytochemistry, 0.5-1 μg/mL Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells

Comment:

Applications are recommended based on the unconjugated antibody.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for VWF

Target: VWF (Von Willebrand Factor (VWF))

Alternative Name: VWF

Background:

Background: Von Willebrand factor (VWF) is a blood glycoprotein involved in hemostasis. It is mapped to 12p13.31. The VWF gene encodes von Willebrand factor (VWF), a large multimeric glycoprotein that plays a central role in the blood coagulation system, serving both as a major mediator of platelet-vessel wall interaction and platelet adhesion, and as a carrier for coagulation factor VIII. VWF released from endothelial cell Weibel-Palade bodies bound particularly avidly to the extracellular matrix. VWF deficiency or dysfunction (von Willebrand disease) leads to a bleeding tendency, which is most apparent in tissues having high blood flow shear in narrow vessels.

Gene Full Name: von Willebrand factor

Sequence Similarities: Contains 1 CTCK (C-terminal cystine knot-like) domain.

Gene ID: 7450

UniProt: P04275