WWTR1 antibody (AA 1-396) (APC)

Catalog No. ABIN8054565

The Rabbit Polyclonal anti-WWTR1 antibody is suitable to detect WWTR1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for WWTR1 antibody (AA 1-396) (APC) (ABIN8054565)

Target: WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This WWTR1 antibody is conjugated to APC

Application: Flow Cytometry (FACS)

Product Details anti-WWTR1 Antibody (APC)

Binding Specificity: AA 1-396

Purpose: Anti-WWTR1 Antibody APC Conjugated

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human WWTR1 recombinant protein (Position: M1-F396).

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for WWTR1

Target: WWTR1 (WW Domain Containing Transcription Regulator 1 (WWTR1))

Alternative Name: WWTR1

Background:

Background: WW domain-containing transcription regulator protein 1 (WWTR1), also known as Transcriptional coactivator with PDZ-binding motif (TAZ), is a protein that in humans is encoded by the WWTR1 gene. WWTR1 acts as a transcriptional coregulator and has no effect on transcription alone. When in complex with transcription factor binding partners, WWTR1 helps promote gene expression in pathways associated with development, cell growth and survival, and inhibiting apoptosis. Aberrant WWTR1 function has been implicated for its role in driving cancers. WWTR1 is often referred to as TAZ due to its initial characterization with the name TAZ. However, WWTR1 (TAZ) is not to be confused with the protein tafazzin, which originally held the official gene symbol TAZ, and is now TAFAZZIN.

Gene Full Name: WW domain containing transcription regulator 1

Gene ID: 25937

UniProt: Q9GZV5

Pathways: Regulation of Lipid Metabolism by PPARalpha