YBX1 antibody (Middle Region) (Biotin)

Catalog No. ABIN8054855

This Rabbit Polyclonal antibody specifically detects YBX1 in WB, IHC and ELISA. It exhibits reactivity toward Rat and Mouse.

Quick Overview for YBX1 antibody (Middle Region) (Biotin) (ABIN8054855)

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Reactivity: Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YBX1 antibody is conjugated to Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Product Details anti-YBX1 Antibody (Biotin)

Binding Specificity: Middle Region

Purpose: Anti-YB1/Ybx1 Antibody Biotin Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Predicted Reactivity: identical to the related rat sequences.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of mouse YB1/Ybx1, identical to the related rat sequences.

Isotype: IgG

Application Details

Application Notes: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Expiry Date: 12 months

Target Details for YBX1

Target: YBX1 (Y Box Binding Protein 1 (YBX1))

Alternative Name: Ybx1

Background:

Background: Y box binding protein 1 also known as Y-box transcription factor or nuclease-sensitive element-binding protein 1 is a protein that in humans is encoded by the YBX1 gene. Enables chromatin binding activity, mRNA binding activity, and single-stranded DNA binding activity. Involved in epidermis development and negative regulation of cellular senescence. Acts upstream of or within several processes, including cellular response to interleukin-7, negative regulation of striated muscle cell differentiation, and negative regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Part of histone pre-mRNA 3'end processing complex. Is expressed in several structures, including branchial arch, central nervous system, facial prominence, gonad, and retina. Orthologous to human YBX1 (Y-box binding protein 1).

Gene Full Name: Y box protein 1

Gene ID: 22608

UniProt: P62960

Pathways: Regulation of Muscle Cell Differentiation