ZEB1 antibody (Middle Region) (Fluoro550)

Catalog No. ABIN8055188

This Mouse Monoclonal antibody specifically detects ZEB1 in FACS. It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for ZEB1 antibody (Middle Region) (Fluoro550) (ABIN8055188)

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZEB1 antibody is conjugated to Fluoro550

Application: Flow Cytometry (FACS)

Clone: 8B12D7

Product Details anti-ZEB1 Antibody (Fluoro550)

Binding Specificity: Middle Region

Purpose: Anti-AREB6/ZEB1 Antibody (monoclonal, 8B12D7) Fluoro550 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human AREB6/ZEB1.

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ZEB1

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Alternative Name: ZEB1

Background:

Background: ZEB1 (Zinc Finger E Box-Binding Homeobox 1), also called TCF8, NIL2A or DELTA-EF1, is a protein that in humans is encoded by the ZEB1 gene. Fluorescence in situ hybridization localized the ZEB1 gene to chromosome 10p11.2. Krafchak et al. (2005) demonstrated a complex (core plus secondary) binding site for TCF8 in the promoter of the COL4A3 gene, mutant in Alport syndrome and which encodes collagen type IV alpha-3. They detected expression of TCF8 in cornea. Nishimura et al. (2006) found that delta-Ef1 was upregulated during differentiation in a mouse smooth muscle cell (SMC) line.

Gene Full Name: zinc finger E-box binding homeobox 1

Gene ID: 6935

UniProt: P37275

Pathways: Regulation of Muscle Cell Differentiation