ZEB1 antibody (Middle Region) (Fluoro594)

Catalog No. ABIN8055189

The Mouse Monoclonal anti-ZEB1 antibody is suitable to detect ZEB1 in samples from Human, Mouse and Rat. It has been validated for FACS.

Quick Overview for ZEB1 antibody (Middle Region) (Fluoro594) (ABIN8055189)

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Reactivity: Human, Mouse, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This ZEB1 antibody is conjugated to Fluoro594

Application: Flow Cytometry (FACS)

Clone: 8B12D7

Product Details anti-ZEB1 Antibody (Fluoro594)

Binding Specificity: Middle Region

Purpose: Anti-AREB6/ZEB1 Antibody (monoclonal, 8B12D7) Fluoro594 Conjugated

Cross-Reactivity (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human AREB6/ZEB1.

Isotype: IgG2b

Application Details

Application Notes: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Expiry Date: 12 months

Target Details for ZEB1

Target: ZEB1 (Zinc Finger E-Box Binding Homeobox 1 (ZEB1))

Alternative Name: ZEB1

Background:

Background: ZEB1 (Zinc Finger E Box-Binding Homeobox 1), also called TCF8, NIL2A or DELTA-EF1, is a protein that in humans is encoded by the ZEB1 gene. Fluorescence in situ hybridization localized the ZEB1 gene to chromosome 10p11.2. Krafchak et al. (2005) demonstrated a complex (core plus secondary) binding site for TCF8 in the promoter of the COL4A3 gene, mutant in Alport syndrome and which encodes collagen type IV alpha-3. They detected expression of TCF8 in cornea. Nishimura et al. (2006) found that delta-Ef1 was upregulated during differentiation in a mouse smooth muscle cell (SMC) line.

Gene Full Name: zinc finger E-box binding homeobox 1

Gene ID: 6935

UniProt: P37275

Pathways: Regulation of Muscle Cell Differentiation