GIP antibody

Catalog No. ABIN8065467

The Mouse Monoclonal anti-GIP antibody is suitable to detect GIP in samples from Human. It has been validated for IHC and ELISA.

Quick Overview for GIP antibody (ABIN8065467)

Target: GIP (Gastric Inhibitory Polypeptide (GIP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This GIP antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Grade: Carrier-free

Clone: 4

Product Details anti-GIP Antibody

Purpose: Anti-Gastric Inhibitory Polypeptide Antibody

Specificity: ABIN8065467 binds human GIP. ABIN8065467 cross-reacts up to 10 % with PACAP and human GLP-2 but <0.1 % with glucagon, GLP-1 or VIP.

Predicted Reactivity: Human

Purification: Protein A or Protein G purified

Immunogen: Synthetic human gastric inhibitory polypeptide

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C without exposure to light

Expiry Date: 24 months

Target Details for GIP

Target: GIP (Gastric Inhibitory Polypeptide (GIP))

Alternative Name: Gastric Inhibitory Polypeptide

Background: GIP, gastric inhibitory polypeptide, glucose-dependent insulinotropic polypeptide, incretin hormone,Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.,GIP,Human gastric inhibitory polypeptide (GIP) is a 42 amino acid peptide belonging to the glucagon-secretin family of peptide hormones. It is secreted by endocrine cells in the duodenal mucosa and stimulates glucose-dependent insulin secretion as well as GLP-1 release from more distal endocrine (L) cells in the intestinal mucosa. GIP shows amino-acid sequence similarities to glucagon, GLP-1 and GLP-2 (from approximately 50 % identity for glucagon to 30 % identity for GLP-2).

Molecular Weight: 17 kDa

Gene ID: 2695

UniProt: P09681

Pathways: Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Regulation of Lipid Metabolism by PPARalpha, Lipid Metabolism