Peptide YY antibody
Quick Overview for Peptide YY antibody (ABIN8065518)
Target
See all Peptide YY (PYY) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Grade
Clone
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Purpose
- Anti-Peptide YY Antibody
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Specificity
- ABIN8065517 binds human PYY. Cross-reactivity with NPY or PP in solution is <0.1 % .
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Predicted Reactivity
- Human
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Purification
- Protein A or Protein G purified
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Immunogen
- Synthetic human PYY
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Isotype
- IgG1, kappa
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- 0.01 M phosphate buffer, pH 7.4, with 0.14 M NaCl and 15 mM sodium azide
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Preservative
- Sodium azide
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Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- 2-8°C without exposure to light
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Expiry Date
- 12 months
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- Peptide YY (PYY)
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Alternative Name
- Peptide YY
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Background
- PYY, PYY-I, PYY1, peptide YY, peptide tyrosine tyrosine, prepro-PYY,This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.,PYY,Peptide tyrosine-tyrosine (PYY) amide is a 36 amino acid. PYY is a member of the pancreatic polypeptide (PP) family of peptides (neuropeptide Y (NPY), PYY and PP). While NPY is localized in neurons (both in the central and peripheral nervous system) and PP in the pancreatic islets, PYY is found in both neurons and the gut. PYY is released in response to food intake from the same endocrine cells (L cells) in the intestinal mucosa as the glucagon-like peptides and inhibits gall bladder secretion, gut motility, and pancreatic secretion. These effects are similar to those of PP and overlap with the gut inhibitory activity of GLP-1.
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Molecular Weight
- 10 kDa (preproprotein), 5 kDa (mature pepide)
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Gene ID
- 5697
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UniProt
- P10082
Target
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