Peptide YY antibody (N-Term)

Catalog No. ABIN8065519

The Mouse Monoclonal anti-Peptide YY antibody (Clone 4) (ABIN8065519) specifically detects Peptide YY in ELISA and WB. The antibody is reactive with Human samples.

Quick Overview for Peptide YY antibody (N-Term) (ABIN8065519)

Target: Peptide YY (PYY)

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This Peptide YY antibody is un-conjugated

Application: ELISA, Western Blotting (WB)

Grade: Carrier-free

Clone: 4

Product Details anti-Peptide YY Antibody

Binding Specificity: N-Term

Purpose: Anti-PYY (3-36) (peptide tyrosine-tyrosine amide, 3-36) Antibody

Specificity: ABIN8065519 binds human PYY(3-36). Based on inhibition ELISA, ABIN8065519 shows no cross-reaction with PYY(1-36) or NPY. The epitope lies within residues 3-12 of human PYY.

Predicted Reactivity: Human

Purification: Protein A or Protein G purified

Immunogen: Synthetic N-terminal fragment of human PYY(3-36) coupled to carrier.

Isotype: IgG2a, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C without exposure to light

Expiry Date: 24 months

Target Details for Peptide YY

Target: Peptide YY (PYY)

Alternative Name: PYY

Background: PYY, PYY-I, PYY1, peptide YY, peptide tyrosine tyrosine, prepro-PYY,This gut peptide inhibits exocrine pancreatic secretion, has a vasoconstrictory action and inhibitis jejunal and colonic mobility.,PYY,Peptide tyrosine-tyrosine amide (3-36), or PYY(3-36), is a major metabolite of the gut hormone PYY and is produced by the action of dipeptidyl peptidase IV on PYY in the intestinal brush border and in the circulation. PYY(3-36) is a potent inhibitor of food intake in rats and humans, acting selectively on the Y2 receptor to inhibit orexigenic NPY neurons in the arcuate nucleus, thus disinhibiting anorexigenic POMC neurons. The anorexigenic effect of PYY(3-36) is additive to that of the co-secreted gut hormone GLP-1.

Molecular Weight: 4 kDa

Gene ID: 5697

UniProt: P10082