PIIaNP antibody (N-Term)

Catalog No. ABIN8065523

This Mouse Monoclonal antibody specifically detects PIIaNP in IHC and ELISA. It exhibits reactivity toward Human.

Quick Overview for PIIaNP antibody (N-Term) (ABIN8065523)

Target: PIIaNP (Procollagen IIa N-Terminal Propeptide (PIIaNP))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PIIaNP antibody is un-conjugated

Application: Immunohistochemistry (IHC), ELISA

Grade: Carrier-free

Clone: 2

Product Details anti-PIIaNP Antibody

Binding Specificity: N-Term

Purpose: Anti-Procollagen Type IIA N-terminal Propeptide (PIIANP) Antibody

Specificity: BTE 003-02 is specific for human PIIANP. Epitope is located at the amino-terminal part of procollagen type IIA

Predicted Reactivity: Human

Purification: Protein A or Protein G purified

Immunogen: Recombinant expressed PIIANP

Isotype: IgG1, kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.01 M phosphate buffer, pH 7.4, with 0.5 M NaCl and 15 mM sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: 2-8°C without exposure to light

Expiry Date: 24 months

Target Details for PIIaNP

Target: PIIaNP (Procollagen IIa N-Terminal Propeptide (PIIaNP))

Alternative Name: Procollagen Type IIA Propeptide

Background: COL2A1, ACG2, ANFH, ANFH1, AOM, COL11A3, EDMMD, LCPD, OSCDP, PLSDT, SEDC, SEDSTN, SEMDSTWK, SMDALG, STL1, VPED, collagen alpha-1(II) chain, alpha-1 type II collagen, arthroophthalmopathy, progressive (Stickler syndrome), cartilage collagen, chondrocalcin, collagen II, alpha-1 polypeptide, collagen, type II, alpha 1,Type II collagen is specific for cartilaginous tissues. It is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces.,COL2A1,Collagen type II is the most abundant protein of cartilage matrix. Two isoforms exist and collagen type IIA is involved in early development of cartilage in embryos. The collagen is produced from type II procollagen when two teloterminal propeptides are digested from the procursor and released into the circulation. Procollagen type II N-terminal propeptide (PIIANP) is considered a marker of cartilage synthesis and the normal concentration in serum is approximately 30 ng/mL.

Molecular Weight: 100 kDa (native trimeric), 19 kDa (monomer)

Gene ID: 1280

UniProt: P02458