ATG4D antibody (pSer467) (Biotin)

Catalog No. ABIN756369

This anti-ATG4D antibody is a Rabbit Polyclonal antibody detecting ATG4D in WB, ELISA, IHC (p) and IHC (fro). Suitable for Mouse.

Quick Overview for ATG4D antibody (pSer467) (Biotin) (ABIN756369)

Target: ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATG4D antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-ATG4D Antibody (Biotin)

Binding Specificity: pSer467

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Rat,Dog,Cow,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated syntheticphosphopeptide derived from human ATG4D around the phosphorylation site of Ser467 [RP(p-S)SE]

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for ATG4D

Target: ATG4D (Autophagy related 4D Cysteine Peptidase (ATG4D))

Alternative Name: ATG4D

Background:

Synonyms: APG4 D, APG4D, ATG4 autophagy related 4 homolog D, Atg4dl, AUT like 4 cysteine endopeptidase, AUTL4, Autophagin 4, Autophagy related cysteine endopeptidase 4, Autophagy related protein 4 homolog D, Cysteine protease ATG4D.

Background: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. [provided by RefSeq].

Gene ID: 84971

Pathways: Autophagy