DAZAP1 antibody (AA 1-189)

Catalog No. ABIN8093125

This Rabbit Polyclonal antibody specifically detects DAZAP1 in WB, ELISA and IHC (p). It exhibits reactivity toward Human, Mouse and Rat.

Quick Overview for DAZAP1 antibody (AA 1-189) (ABIN8093125)

Target: DAZAP1 (DAZ Associated Protein 1 (DAZAP1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DAZAP1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-DAZAP1 Antibody

Binding Specificity: AA 1-189

Purpose: DAZAP1 Antibody / DAZ-associated protein 1

Purification: Affinity purified

Immunogen: Amino acids M1-E189 from the human protein were used as the immunogen for the DAZAP1 antibody.

Isotype: IgG

Application Details

Application Notes: Optimal dilution of the DAZAP1 antibody should be determined by the researcher.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Storage: -20 °C

Storage Comment: Store the DAZAP1 antibody at -20oC.

Target Details for DAZAP1

Target: DAZAP1 (DAZ Associated Protein 1 (DAZAP1))

Alternative Name: DAZAP1

Background: DAZAP1 Antibody targets DAZ-associated protein 1, an RNA-binding protein encoded by the DAZAP1 gene that plays a role in post-transcriptional regulation of gene expression. DAZ-associated protein 1 was originally identified through its interaction with DAZ family proteins and is now recognized as a broadly expressed factor involved in RNA processing, transport, and stability. Through these activities, DAZAP1 contributes to fine control of mRNA metabolism and cellular gene expression programs.

Functionally, DAZ-associated protein 1 binds RNA through conserved RNA recognition motifs that enable sequence-specific interactions with target transcripts. These interactions allow DAZAP1 to influence alternative splicing, mRNA localization, and translational efficiency depending on cellular context. A DAZAP1 Antibody enables investigation of RNA-binding protein function and post-transcriptional regulatory mechanisms that shape gene expression in both normal and disease-associated settings.

DAZAP1 expression is observed in many tissues and cell types, reflecting its role in fundamental RNA regulatory processes. At the subcellular level, DAZ-associated protein 1 is predominantly localized to the nucleus, where it associates with pre-mRNA processing complexes and splicing machinery. Cytoplasmic localization has also been reported, consistent with additional roles in mRNA transport and translation. Changes in DAZAP1 localization may reflect shifts in RNA metabolism or cellular responses to developmental or stress-related cues.

At the molecular level, DAZ-associated protein 1 contains RNA recognition motif domains that mediate binding to single-stranded RNA. These domains allow DAZAP1 to interact with diverse RNA species and participate in multiple steps of post-transcriptional regulation. DAZAP1 also interacts with other RNA-binding proteins and regulatory factors, enabling formation of ribonucleoprotein complexes that coordinate RNA processing events. Regulation of DAZAP1 activity may involve post-translational modifications that influence its interactions and cellular distribution.

From a biological and disease relevance perspective, DAZAP1 has been studied in the context of cell proliferation, differentiation, and stress responses, where precise control of RNA processing is essential. Altered expression or function of RNA-binding proteins such as DAZAP1 has been associated with dysregulated gene expression programs in cancer and other diseases. As a result, DAZAP1 is of interest as a component of RNA regulatory networks that contribute to cellular homeostasis and disease-associated transcriptional remodeling.

DAZAP1 Antibody reagents are valuable tools for studying RNA-binding protein biology, post-transcriptional regulation, and mechanisms of mRNA processing. These antibodies support research into RNA metabolism, nuclear organization, and disease-associated alterations in gene expression control. NSJ Bioreagents provides DAZAP1 Antibody products intended for research use.

UniProt: Q96EP5