COX6A2 antibody (Middle Region)

Catalog No. ABIN8098337

The Rabbit Polyclonal anti-COX6A2 antibody is suitable to detect COX6A2 in samples from Human. It has been validated for WB.

Quick Overview for COX6A2 antibody (Middle Region) (ABIN8098337)

Target: COX6A2 (Cytochrome C Oxidase Subunit VIa Polypeptide 2 (COX6A2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX6A2 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-COX6A2 Antibody

Binding Specificity: Middle Region

Purpose: COX6A2 Antibody - middle region

Sequence: ALPSVALCTF NSYLHSGHRP RPEFRPYQHL RIRTKPYPWG DGNHTLFHNS

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human CX6A2

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP76032-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for COX6A2

Target: COX6A2 (Cytochrome C Oxidase Subunit VIa Polypeptide 2 (COX6A2))

Alternative Name: COX6A2

Background:

Background Information: Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 2 (heart/muscle isoform) of subunit VIa, and polypeptide 2 is present only in striated muscles. Polypeptide 1 (liver isoform) of subunit VIa is encoded by a different gene, and is found in all non-muscle tissues. These two polypeptides share 66 % amino acid sequence identity.

Gene Name: cytochrome c oxidase subunit 6A2

Alternative Symbols: COX6AH, COXVIAH, MC4DN18

Protein Name: cytochrome c oxidase subunit 6A2, mitochondrial

Molecular Weight: 10 kDa

Gene ID: 1339

NCBI Accession: NP_005196

UniProt: Q02221