GABRA6 antibody (N-Term)

Catalog No. ABIN8101268

The Rabbit Polyclonal anti-GABRA6 antibody is suitable to detect GABRA6 in samples from Human, Cow, Dog, Horse, Pig and Rabbit. It has been validated for WB.

Quick Overview for GABRA6 antibody (N-Term) (ABIN8101268)

Target: GABRA6 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 6 (GABRA6))

Reactivity: Human, Cow, Dog, Horse, Pig, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRA6 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GABRA6 Antibody

Binding Specificity: N-Term

Purpose: GABRA6 Antibody - N-terminal region

Sequence: ENALGKLEVE GNFYSENVSR ILDNLLEGYD NRLRPGFGGA VTEVKTDIYV

Predicted Reactivity: Cow: 92%, Dog: 92%, Horse: 93%, Human: 100%, Pig: 93%, Rabbit: 79%

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human GBRA6

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34985-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GABRA6

Target: GABRA6 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 6 (GABRA6))

Alternative Name: GABRA6

Background:

Background Information: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.

Gene Name: gamma-aminobutyric acid type A receptor alpha6 subunit

Protein Name: gamma-aminobutyric acid receptor subunit alpha-6

Molecular Weight: 49kDa

Gene ID: 2559

NCBI Accession: NP_000802

UniProt: Q16445

Pathways: Synaptic Membrane