GUCY1A1 antibody (C-Term)

Catalog No. ABIN8102104

This Rabbit Polyclonal antibody specifically detects GUCY1A1 in WB. It exhibits reactivity toward Human.

Quick Overview for GUCY1A1 antibody (C-Term) (ABIN8102104)

Target: GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GUCY1A1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GUCY1A1 Antibody

Binding Specificity: C-Term

Purpose: GUCY1A1 Antibody - C-terminal region

Sequence: DCPGFVFTPR SREELPPNFP SEIPGICHFL DAYQQGTNSK PCFQKKDVED

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human GCYA3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP76246-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for GUCY1A1

Target: GUCY1A1 (Guanylate Cyclase 1 Soluble Subunit Alpha (GUCY1A1))

Alternative Name: GUCY1A1

Background:

Background Information: Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.

Gene Name: guanylate cyclase 1 soluble subunit alpha 1

Alternative Symbols: GUCA3, MYMY6, GC-SA3, GUC1A3, GUCSA3, GUCY1A3, GCS-alpha-3, GC-S-alpha-1

Protein Name: guanylate cyclase soluble subunit alpha-1

Molecular Weight: 77kDa

Gene ID: 2982

NCBI Accession: XP_006714260

UniProt: Q02108

Pathways: Myometrial Relaxation and Contraction