HRC antibody (C-Term)

Catalog No. ABIN8102555

The Rabbit Polyclonal anti-HRC antibody is suitable to detect HRC in samples from Human, Mouse, Guinea Pig, Cow, Dog, Goat, Horse, Rabbit, Rat and Saccharomyces cerevisiae. It has been validated for WB.

Quick Overview for HRC antibody (C-Term) (ABIN8102555)

Target: HRC (Histidine Rich Calcium Binding Protein (HRC))

Reactivity: Human, Mouse, Guinea Pig, Cow, Dog, Goat, Horse, Rabbit, Rat, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HRC antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-HRC Antibody

Binding Specificity: C-Term

Purpose: HRC Antibody - C-terminal region

Sequence: EQGEKGTHHG SRDQEDEEDE EEGHGLSLNQ EEEEEEDKEE EEEEEDEERR

Predicted Reactivity: Cow: 90%, Dog: 90%, Goat: 90%, Guinea Pig: 100%, Horse: 90%, Human: 100%, Mouse: 90%, Rabbit: 82%, Rat: 90%, Yeast: 90%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SRCH

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP41495-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for HRC

Target: HRC (Histidine Rich Calcium Binding Protein (HRC))

Alternative Name: HRC

Background:

Background Information: This gene encodes a luminal sarcoplasmic reticulum protein identified by its ability to bind low-density lipoprotein with high affinity. The protein interacts with the cytoplasmic domain of triadin, the main transmembrane protein of the junctional sarcoplasmic reticulum (SR) of skeletal muscle. The protein functions in the regulation of releasable calcium into the SR.

Gene Name: histidine rich calcium binding protein

Alternative Symbols: HCP

Protein Name: sarcoplasmic reticulum histidine-rich calcium-binding protein

Molecular Weight: 76kDa

Gene ID: 3270

NCBI Accession: NP_002143

UniProt: P23327