IFT122 antibody (Middle Region)

Catalog No. ABIN8103429

The Rabbit Polyclonal anti-IFT122 antibody (ABIN8103429) specifically detects IFT122 in WB. The antibody is reactive with Human samples.

Quick Overview for IFT122 antibody (Middle Region) (ABIN8103429)

Target: IFT122 (Intraflagellar Transport 122 (IFT122))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IFT122 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IFT122 Antibody

Binding Specificity: Middle Region

Purpose: IFT122 Antibody - middle region

Sequence: QDLRYLELIS SIEERKKRGE TNNDLFLADV FSYQGKFHEA AKLYKRSGHE

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IFT122

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP53816-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for IFT122

Target: IFT122 (Intraflagellar Transport 122 (IFT122))

Alternative Name: IFT122

Background:

Background Information: This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation. Mutations in this gene cause cranioectodermal dysplasia-1. A related pseudogene is located on chromosome 3. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Name: intraflagellar transport 122

Alternative Symbols: CED, SPG, CED1, FAP80, WDR10, WDR10p, WDR140

Protein Name: Intraflagellar transport protein 122 homolog

Molecular Weight: 130 kDa

Gene ID: 55764

NCBI Accession: NP_443715

UniProt: Q9HBG6

Pathways: Tube Formation, Embryonic Body Morphogenesis