MPP1 antibody (C-Term)

Catalog No. ABIN8105142

The Rabbit Polyclonal anti-MPP1 antibody (ABIN8105142) specifically detects MPP1 in WB. The antibody is reactive with Human samples.

Quick Overview for MPP1 antibody (C-Term) (ABIN8105142)

Target: MPP1 (Membrane Protein, Palmitoylated 1, 55kDa (MPP1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MPP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MPP1 Antibody

Binding Specificity: C-Term

Purpose: MPP1 Antibody - C-terminal region

Sequence: PVPYTTRPPR KSEEDGKEYH FISTEEMTRN ISANEFLEFG SYQGNMFGTK

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human EM55

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74070-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for MPP1

Target: MPP1 (Membrane Protein, Palmitoylated 1, 55kDa (MPP1))

Alternative Name: MPP1

Background:

Background Information: This gene encodes the prototype of the membrane-associated guanylate kinase (MAGUK) family proteins. MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intercellular junctions. The encoded protein is an extensively palmitoylated membrane phosphoprotein containing a PDZ domain, a Src homology 3 (SH3) motif, and a guanylate kinase domain. This gene product interacts with various cytoskeletal proteins and cell junctional proteins in different tissue and cell types, and may be involved in the regulation of cell shape, hair cell development, neural patterning of the retina, and apico-basal polarity and tumor suppression pathways in non-erythroid cells. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: membrane palmitoylated protein 1

Alternative Symbols: MRG1, PEMP, AAG12, EMP55, DXS552E

Protein Name: 55 kDa erythrocyte membrane protein

Molecular Weight: 51kDa

Gene ID: 4354

NCBI Accession: NP_002427

UniProt: Q00013