CHRNB1 antibody (N-Term)

Catalog No. ABIN8106489

The Rabbit Polyclonal anti-CHRNB1 antibody (ABIN8106489) specifically detects CHRNB1 in WB. The antibody is reactive with Human, Rat, Cow, Guinea Pig, Horse, Rabbit and Dog samples.

Quick Overview for CHRNB1 antibody (N-Term) (ABIN8106489)

Target: CHRNB1 (Nicotinic Acetylcholine Receptor beta (CHRNB1))

Reactivity: Human, Rat, Cow, Guinea Pig, Horse, Rabbit, Dog

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CHRNB1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-CHRNB1 Antibody

Binding Specificity: N-Term

Purpose: CHRNB1 Antibody - N-terminal region

Sequence: PLAPGVRGSE AEGRLREKLF SGYDSSVRPA REVGDRVRVS VGLILAQLIS

Predicted Reactivity: Cow: 100%, Dog: 85%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 100%, Rat: 100%

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human ACHB

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP34969-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for CHRNB1

Target: CHRNB1 (Nicotinic Acetylcholine Receptor beta (CHRNB1))

Alternative Name: CHRNB1

Background:

Background Information: The muscle acetylcholine receptor is composed of five subunits: two alpha subunits and one beta, one gamma, and one delta subunit. This gene encodes the beta subunit of the acetylcholine receptor. The acetylcholine receptor changes conformation upon acetylcholine binding leading to the opening of an ion-conducting channel across the plasma membrane. Mutations in this gene are associated with slow-channel congenital myasthenic syndrome.

Gene Name: cholinergic receptor nicotinic beta 1 subunit

Alternative Symbols: ACHRB, CHRNB, CMS1D, CMS2A, CMS2C, SCCMS

Protein Name: acetylcholine receptor subunit beta

Molecular Weight: 55kDa

Gene ID: 1140

NCBI Accession: NP_000738

UniProt: P11230

Pathways: Synaptic Membrane