PDLIM7 antibody (Middle Region)

Catalog No. ABIN8107737

The Rabbit Polyclonal anti-PDLIM7 antibody (ABIN8107737) specifically detects PDLIM7 in WB. The antibody is reactive with Human samples.

Quick Overview for PDLIM7 antibody (Middle Region) (ABIN8107737)

Target: PDLIM7 (PDZ and LIM Domain 7 (Enigma) (PDLIM7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PDLIM7 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PDLIM7 Antibody

Binding Specificity: Middle Region

Purpose: PDLIM7 Antibody - middle region

Sequence: SSTPQEPWPG PTAPSPTSRP PWAVDPAFAE RYAPDKTSTV LTRHSQPATP

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human PDLI7

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74121-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PDLIM7

Target: PDLIM7 (PDZ and LIM Domain 7 (Enigma) (PDLIM7))

Alternative Name: PDLIM7

Background:

Background Information: The protein encoded by this gene is representative of a family of proteins composed of conserved PDZ and LIM domains. LIM domains are proposed to function in protein-protein recognition in a variety of contexts including gene transcription and development and in cytoskeletal interaction. The LIM domains of this protein bind to protein kinases, whereas the PDZ domain binds to actin filaments. The gene product is involved in the assembly of an actin filament-associated complex essential for transmission of ret/ptc2 mitogenic signaling. The biological function is likely to be that of an adapter, with the PDZ domain localizing the LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Alternative splicing of this gene results in multiple transcript variants.

Gene Name: PDZ and LIM domain 7

Alternative Symbols: LMP1, LMP3

Protein Name: PDZ and LIM domain protein 7

Molecular Weight: 50kDa

Gene ID: 9260

UniProt: Q9NR12