PRODH antibody (N-Term)

Catalog No. ABIN8108981

The Rabbit Polyclonal anti-PRODH antibody is suitable to detect PRODH in samples from Human. It has been validated for WB.

Quick Overview for PRODH antibody (N-Term) (ABIN8108981)

Target: PRODH (Proline Dehydrogenase (Oxidase) 1 (PRODH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRODH antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PRODH Antibody

Binding Specificity: N-Term

Purpose: PRODH Antibody - N-terminal region

Sequence: EAEHKEMESC TSAAERDGSG TNKRDKQYQA HRAFGDRRNG VISARTYFYA

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human PROD

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP74149-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PRODH

Target: PRODH (Proline Dehydrogenase (Oxidase) 1 (PRODH))

Alternative Name: PRODH

Background:

Background Information: This gene encodes a mitochondrial protein that catalyzes the first step in proline degradation. Mutations in this gene are associated with hyperprolinemia type 1 and susceptibility to schizophrenia 4 (SCZD4). This gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes, DiGeorge and CATCH22. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: proline dehydrogenase 1

Alternative Symbols: POX, PIG6, HSPOX2, PRODH1, PRODH2, TP53I6

Protein Name: proline dehydrogenase 1, mitochondrial

Molecular Weight: 66kDa

Gene ID: 5625

NCBI Accession: NP_057419

UniProt: O43272

Pathways: Response to Water Deprivation, Monocarboxylic Acid Catabolic Process