PRKD3 antibody (Middle Region)

Catalog No. ABIN8109315

The Rabbit Polyclonal anti-PRKD3 antibody (ABIN8109315) specifically detects PRKD3 in WB. The antibody is reactive with Human samples.

Quick Overview for PRKD3 antibody (Middle Region) (ABIN8109315)

Target: PRKD3 (Protein Kinase D3 (PRKD3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRKD3 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PRKD3 Antibody

Binding Specificity: Middle Region

Purpose: PRKD3 Antibody - middle region

Sequence: VHYTSRDNLR KRHYWRLDSK CLTLFQNESG SKYYKEIPLS EILRISSPRD

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human KPCD3

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP75493-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PRKD3

Target: PRKD3 (Protein Kinase D3 (PRKD3))

Alternative Name: PRKD3

Background:

Background Information: This gene belongs to the multigene protein kinase D family of serine/threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N-terminal regulatory domain comprised of a tandem repeat of cysteine-rich zinc-finger motifs and a pleckstrin domain. The C-terminal region contains the catalytic domain and is distantly related to calcium-regulated kinases. Catalytic activity of this enzyme promotes its nuclear localization. This protein has been implicated in a variety of functions including negative regulation of human airway epithelial barrier formation, growth regulation of breast and prostate cancer cells, and vesicle trafficking.

Gene Name: protein kinase D3

Alternative Symbols: EPK2, PKD3, PRKCN, PKC-NU, nPKC-NU

Protein Name: serine/threonine-protein kinase D3

Molecular Weight: 97kDa

Gene ID: 23683

NCBI Accession: XP_005264294

UniProt: O94806