PCDHGC5 antibody (N-Term)

Catalog No. ABIN8109592

This Rabbit Polyclonal antibody specifically detects PCDHGC5 in WB. It exhibits reactivity toward Human.

Quick Overview for PCDHGC5 antibody (N-Term) (ABIN8109592)

Target: PCDHGC5 (Protocadherin gamma Subfamily C, 5 (PCDHGC5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PCDHGC5 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PCDHGC5 Antibody

Binding Specificity: N-Term

Purpose: PCDHGC5 Antibody - N-terminal region

Sequence: IVLDINDNAP TFQSSVLRVG IPENAPIGTL LLRLNATDPD EGTNGQLDYS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 93%, Rat: 100%, Zebrafish: 100%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the n terminal region of human PCDHGC5

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP49391-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for PCDHGC5

Target: PCDHGC5 (Protocadherin gamma Subfamily C, 5 (PCDHGC5))

Alternative Name: PCDHGC5

Background:

Background Information: This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.

Gene Name: protocadherin gamma subfamily C, 5

Alternative Symbols: PCDH-GAMMA-C5

Protein Name: Protocadherin gamma-C5

Molecular Weight: 95 kDa

Gene ID: 56097

NCBI Accession: NP_061752

UniProt: Q9Y5F6