RASSF8 antibody (N-Term)

Catalog No. ABIN8110027

This Rabbit Polyclonal antibody specifically detects RASSF8 in WB. It exhibits reactivity toward Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit and Zebrafish (Danio rerio).

Quick Overview for RASSF8 antibody (N-Term) (ABIN8110027)

Target: RASSF8 (Ras Association (RalGDS/AF-6) Domain Family (N-terminal) Member 8 (RASSF8))

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RASSF8 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RASSF8 Antibody

Binding Specificity: N-Term

Purpose: RASSF8 Antibody - N-terminal region

Sequence: RHLAPHENPI ISLNKWGQYA SDVQLILRRT GPSLSERPTS DSVARIPERT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human RASF8

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP52302-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for RASSF8

Target: RASSF8 (Ras Association (RalGDS/AF-6) Domain Family (N-terminal) Member 8 (RASSF8))

Alternative Name: RASSF8

Background:

Background Information: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12,22)(p11.2,q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: Ras association domain family member 8

Alternative Symbols: HOJ1, C12orf2

Protein Name: ras association domain-containing protein 8

Molecular Weight: 43kDa

Gene ID: 11228

UniProt: Q8NHQ8

Pathways: Chromatin Binding