SSR1 antibody (C-Term)

Catalog No. ABIN8111724

The Rabbit Polyclonal anti-SSR1 antibody (ABIN8111724) specifically detects SSR1 in WB. The antibody is reactive with Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit and Zebrafish (Danio rerio) samples.

Quick Overview for SSR1 antibody (C-Term) (ABIN8111724)

Target: SSR1 (Signal Sequence Receptor, alpha (SSR1))

Reactivity: Human, Mouse, Rat, Dog, Cow, Horse, Guinea Pig, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SSR1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SSR1 Antibody

Binding Specificity: C-Term

Purpose: SSR1 Antibody - C-terminal region

Sequence: VKFLVGFTNK GTEDFIVESL DASFRYPQDY QFYIQNFTAL PLNTVVPPQR

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Purification: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human SSRA

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP45427-100UG

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: prevent freeze-thaw cycles

Storage: 4 °C,-20 °C

Storage Comment: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Target Details for SSR1

Target: SSR1 (Signal Sequence Receptor, alpha (SSR1))

Alternative Name: SSR1

Background:

Background Information: The signal sequence receptor (SSR) is a glycosylated endoplasmic reticulum (ER) membrane receptor associated with protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein encoded by this gene and a 22-kD glycoprotein. This gene generates several mRNA species as a result of complex alternative polyadenylation. This gene is unusual in that it utilizes arrays of polyA signal sequences that are mostly non-canonical. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Name: signal sequence receptor subunit 1

Alternative Symbols: TRAPA

Protein Name: translocon-associated protein subunit alpha

Molecular Weight: 31kDa

Gene ID: 6745

NCBI Accession: NP_003135

UniProt: P43307

Pathways: ER-Nucleus Signaling